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Sequence data from two genomic regions ( region on chromosome 8) from 15 primate species are used with the birth–death model implemented in mcmctree in PAML to infer the posterior distribution of the ages of 14 nodes in the primate tree.
We find that these age estimates are older than previously reported dates for all but one of these nodes.
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We provide an integrated analysis of palaeontological and molecular data to give estimates of primate divergence times that utilize both sources of information.
The number of preserved primate species discovered in the fossil record, along with their geological age distribution, is combined with the number of extant primate species to provide initial estimates of the primate and anthropoid divergence times.
To perform the inference, a new approximate Bayesian computation (ABC) algorithm is introduced, where the structure of the model can be exploited in an ABC-within-Gibbs algorithm to provide a more efficient analysis.